The value of PET-CT in postoperative colorectal cancer with rising CEA or CA19-9
10.3760/cma.j.issn.1006-9801.2010.05.004
- VernacularTitle:PET-CT在结直肠癌术后CEA、CA19-9升高患者中的应用
- Author:
Binqing ZHANG
;
Rui AN
;
Yongxue ZHANG
;
Xun SUN
;
Tao WU
;
Qing JIA
- Publication Type:Journal Article
- Keywords:
Colorectal neoplasms;
Recurrence;
Neoplasm metastasis;
Positron emission tomography;
18F-FDG;
CEA;
CA 19-9
- From:
Cancer Research and Clinic
2010;22(5):297-299
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical value of 18F-FDG PET-CT in detecting or diagnosing the recurrence and metastasis of colorectal cancer in the postoperative patients with rising CEA or CA19-9 during the follow-up.Methods 87 colorectal cancer patients were entered in the trial,all were postoperative,and during the follow-up were rising CEA or CA19-9 found, and then had the whole body 18F-FDG PET-CT examination.The final diagnosis of all patients were based on pathology results of re-operation,colonoscoply,a variety of imaging examination or clinical follow-up. Results For the diagnosis of recurrence or metastasis of postoperative colorectal cancer with rising CEA or CA19-9,PET-CT sensitivity was 91.0%(71/78),specificity 66.7%(6/9),accuracy 88.5%(77/87).Among the 61 patients who have recently (in 3 months) had conventional chest,abdominal and pelvic imaging examination (ultrasound,CT and MRI),32 patients PET-CT found the lesions that the conventional imaging did not found.The treatment programs of 21 patients have been changed,correction rate was 34.4%(2 1/61). Conclusion The 18F-FDG PET-CT imaging had a significant value in the diagnosis of recurrence and metastasis and restaging in the postoperative colorectal cancer with rising CEA or CA19-9 during the follow-up.
