A clinical study of paraffin-embedded sediments section combined with routine smear in diagnosis of malignant tumor from hydrothorax and hydroperitoneum
10.3760/cma.j.issn.1006-9801.2010.05.008
- VernacularTitle:胸腹腔积液沉淀物石蜡包埋切片法联合常规涂片法的临床研究
- Author:
Yan ZHAO
;
Zhihua YAO
;
Jie MA
;
Tao LIU
;
Yanyan LIU
;
Shujun YANG
- Publication Type:Journal Article
- Keywords:
Pleural effusion,malignant;
Ascites;
Malignant neoplasms;
Immunohistochemistry;
Routine smear;
Paraffin-embedded sediments section
- From:
Cancer Research and Clinic
2010;22(5):308-311
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of paraffin-embedded sediments section combined with routine smear in diagnosis of malignant tumor from hydrothorax and hydroperitoneum.Methods 150 cases of hydrothorax and hydroperitoneum were analyzed by using the methods of paraffin-embedded section and routine smear respectively.Results Among 150 cases with hydrothorax and hydroperitoneum,120 cases were certified malignancy by clinical source and other methods.The positive rate was 62.5% (75/120) by routine smear and 84.2% (101/120) by paraffin-embedded sediments section respectively,while the positive rate was 94.2% (113/120) by the combined examination of the two and the difference was significant compared with routine smear and paraffin-embedded sediments section respectively. At the same time, It is easier for us to distinguish adenocarcinoma cell from mesothelial cell by means of detecting the expression of CEA,CK,CAL and VIM immunohistochemically.Conclusion The combined examination of the two methods along with immunohistochemistry can increase diagnosis rate significantly and worth of being generalized.
