Antihypertensive Effect of Saikokaryukotsuboreito Accompanied by Objective Changes in Autonomic Balance
10.3937/kampomed.59.53
- Author:
Hiroshi ODAGUCHI
;
Akino WAKASUGI
;
Hidenori ITO
;
Hisakazu SHODA
;
Yuji GAMO
;
Koji WATANABE
;
Takayuki HOSHINO
;
Tetsuro OIKAWA
;
Toshihiko HANAWA
- Publication Type:Journal Article
- Keywords:
saikokaryukotsuboreito;
hypertension;
autonomic nerve;
ambulatory blood pressure monitoring (ABPM);
white coat effect;
masked hypertension;
arterial stiffness;
postural test;
insulin resistance
- MeSH:
Blood Pressure;
Assessment of balance;
Hour;
Effective;
Equilibrium
- From:Kampo Medicine
2008;59(1):53-61
- CountryJapan
- Language:Japanese
-
Abstract:
We report the case of a 46-year-old man with hypertension whose blood pressure decreased due to saiko-karyukotsuboreito consumption.The patient also presented with some symptoms that suggested autonomic imbalance. After consuming 7.5g/day of a spray-dried powder of saikokaryukotsuboreito (Tsumura & Co.) for 3 months, his blood pressure measured at office was considerably lower. Twenty-four hour ambulatory blood pressure monitoring revealed that the surge in morning blood pressure, which is considered to be a risk factor for cerebrovascular disease, diminished in addition to the 24-hour mean blood pressure. A postural test revealed that his autonomic balance, which had been in a sympathetic dominant state, was inversely inclined to a parasympathetic dominant state.Our case report suggests that saikokaryukotsuboreito acts on the autonomic nervous system, which in turn exerts an antihypertensive effect, and that this effect is helpful in lowering the blood pressure in hypertensive patients whose autonomic balance is impaired due to stress.
