The Effects of Lactic Fermenting Beverage ANP71 on Defecation-An Open Clinical Trial-
10.1625/jcam.14.39
- VernacularTitle:乳酸菌飲料ANP71の排便状況に及ぼす影響-オープン臨床試験-
- Author:
Hoko KYO
;
Kazuo UEBABA
;
Tetsuro ABE
;
Shintaro HASHIMOTO
;
Tomihisa OHTA
;
Nobutaka SUZUKI
- Keywords:
Lactic fermenting beverage;
Defecation;
Immune function;
Constitution
- From:Japanese Journal of Complementary and Alternative Medicine
2017;14(1):39-44
- CountryJapan
- Language:Japanese
-
Abstract:
Objectives: The aim of this study is to examine the effects of lactic fermenting beverage ANP71 on defecation, blood pressure, immune function, constitution of Traditional Chinese Medicine (TCM) and safety.Methods: An open Clinical study was conducted on 15 healthy adults (female 11, male 4). ANP71 150ml per day was administrated for 4 weeks. At week 0, 1 and 4, blood samples were collected. blood pressure, immune function and constitutionwere measured.Results:① Defecation amount and exhilarating feeling increased. Abdominal feeling of fullness decreased.② Decrease of blood pressure was observed. ③ The change of parameters of blood biochemistry was in normal range. ④ Humoral immunity was predominant(Th1/Th2 decreased). ⑤ In constitution of TCM, Gentleness type, Yang-deficiency type, Yin-deficiency type, Phlegm-wetness type, wet-heat type and Qi-depression type were improved. ⑥ No significant adverse events were observed.Conclusion: Lactic fermenting beverage ANP71 appears to have benefits in improving defecation and constitutional problems. Various other biological effects of ANP71 were also observed.