Effect of Ganoderma lucidum on cholesterol drunk-induced hyperlipidemia rats
- Author:
Nguyen Thi Mai Anh
- Publication Type:Journal Article
- Keywords:
Plasma;
Lipid level;
Hyperlipidemia rats;
Cholesteroldrunk;
Ganoderma lucidum
- MeSH:
Hyperlipidemias;
Ganoderma;
Cholesterol;
Animal Experimentation
- From:Journal of Medical Research
2005;38(5):42-45
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Objectives: To evaluate the influence of Ganoderma lucidum on cholesterol drunk - induced hyperlipidemia rats. Methods: Rats were received cholesterol in the oral daily during 8 consecutive weeks in order to hyperlipidemia rats. From 5th week, extract of Ganoderma lucidum (GL) at the doses of 2g/kg, 4g/kg administered orally was investigated in cholesterol drunk - induced hyperlipidemia rats. Results: GL significantly decreased plasma triglycerid, total cholesterol, LDL - C, but increased HDL - C. The effect of GL on plasma lipid level at the oral doses of 2g/kg, 4g/kg was equal to each other and to Lopid (gemfibrozil) at the dose of 140mg/kg. Conclusions: GL have a hypolipidemia effect on rats.
