Anti-tuberculosis - drugs - related hepatitis
- Author:
Hoang Long Phat
- Publication Type:Journal Article
- Keywords:
hepatitis
- MeSH:
Tuberculosis;
Hepatitis, Chronic, Drug-Induced;
Tuberculosis, Multidrug-Resistant;
drugs
- From:Journal of Medical and Pharmaceutical Information
2003;0(3):5-11
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Most of anti-tuberculosis drugs are hepatic toxicity; especially 3 most common and best efficient drugs R, H, Z. Drug combination resulted in increasing toxicity, adverse events, especially drug-induced hepatitis. The authors reviewed situation of drug-induced hepatitis in the world and introduced one case in Vietnam. He also listed some drug known that have hepatotoxicity such as isoniazid (INH, H); rifampicin (RMP, R); pyrazinamid (PZA, Z); ethambutol (EMB, E); ethionamid (ETB); thiacetazon (TH, Tbl) and their mechanisms. Some experiences in treating and preventing drug-induced hepatitis were introduced
