The hypoglycemic effect of atractylodes macrocephala, lycium sinense and seoparia dulcis on mice
- Author:
Dao Van Phan
- Publication Type:Journal Article
- Keywords:
Anti diabetic drug;
Atractylodes macrocephala;
Lycium sinense;
Seoparia dulcis
- MeSH:
Hypoglycemic Agents;
Blood Glucose;
Mice
- From:Journal of Medical Research
2005;38(5):39-41
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Objectives: To evaluate the hypoglycemic effect of these herbal medicines' on normal mice. Methods: the ethanol extracts of these plants have been introduced intraperitoneally to mice with the dose of 500 mg/kg of body weight. The blood glucose levels were determined by one - touch glucose meter at just (0h) before and at 1h, 2h, 3h, 4h and conclusion after drug administration. Results: Lycium sinense Mill lowered the glycemia by more than 30% in comparison to that of initial level. Separia dulcis, however, caused hyperglycemia (+ 62%) at the first hour then at the 3rd and 4th hour the blood glucose was diminished with>30%. Atractylodes macrocephala did not lower the glycemia.
