Trial of the Dementia Differentiation Questionnaire-41 items (DDQ41) .
10.14442/generalist.39.29
- VernacularTitle:認知症病型分類質問票41項目版 (Dementia differentiation questionnaire-41 items ; DDQ41) の試み
- Author:
Haruyasu Yamaguchi
;
Tomoko Nakajima
;
Haruka Uchida
;
Masakuni Amari
;
Masaki Ikeda
;
Yohko Maki
;
Tomoharu Yamaguchi
;
Rumi Shinohara
;
Masamitsu Takatama
- Publication Type:Journal Article
- Keywords:
dementia;
differentia diagnosis;
typing;
questionnaire;
dementia with Lewy bodies
- From:An Official Journal of the Japan Primary Care Association
2016;39(1):29-36
- CountryJapan
- Language:Japanese
-
Abstract:
Introduction : To detect major symptoms of dementia, especially symptoms of non-Alzheimer-type dementia, we tried to develop an informant-based questionnaire, the Dementia differentiation questionnaire-41 items (DDQ41).
Methods : The DDQ41 consisted of 11 questions on symptoms of early dementia (Q-Dementia11), 8 on Alzheimer's disease dementia(Q-ADD8), 9 on dementia with Lewy bodies (Q-DLB9), 8 on vascular dementia (Q-VD8), 5 on frontal lobe signs (Q-Frontal5), and additional 2 questions on urinary incontinence and speech disturbance. Caregivers of the 575 outpatients, who included only 1 diagnosis of dementia disease, checked the DDQ41.
Results : Mean score of Q-Dementia11 in the MCI group was significantly lower than that in the other dementia groups. Mean score of Q-ADD8 in the ADD group was not significantly different from that in the other dementia groups. Mean score of Q-DLB9 in the DLB group was significantly higher than that in the other dementia groups. Area under the ROC curve of Q-DLB9 was 85.6%, and sensitivity and specificity were 82.6% and 77.7%(cut-off : 3 items/4 items), respectively, for DLB.
Conclusion : We developed the DDQ41, an informant-based questionnaire sheet, for detecting symptoms of dementia. It may be useful in detecting frontal lobe signs and symptoms of non-Alzheimer-type dementia, especially those of DLB.
