Effect of green tea (Camellia sinensis) polyphenol on blood antioxydant status in rats with streptozocin-induced diabetes
- Author:
Nguyen Thi Ha
- Publication Type:Journal Article
- Keywords:
Diabetes;
Green tea;
Polyphenol content;
Antioxydants;
Oxidant stress;
Camellia sinensis
- MeSH:
Diabetes Mellitus;
Tea;
Camellia sinensis;
Blood;
Oxidants
- From:Journal of Medical Research
2005;38(5):27-33
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The diabetic patients are usually suffered from oxidation stress. Green tea is one of the good herbal medicines has been used for treatment of some diseases. Objectives: Evaluate change of antioxidant status in blood and effect of the green tea polyphenol on this change in the experimental diabetic rats. Methods: Using in vivo model to investigate some biological indicators in STZ - induced diabetic rats fed with high fat diet and to evaluate effect of the green tea polyphenol on the changes of these indicators. Results: Erythrocyte GPx activity and serum MDA concentration in STZ - induced diabetic rats was higher than that of normal and lipid metabolism disorder groups (p < 0.001) and effected of the green tea polyphenol. However, no change in erythrocyte SOD activity and plasma TAS level was observed. Conclusions: Green tea polyphenol improved blood antioxidant status in STZ - induced diabetic rats.
