The Effect of Acupuncture Treatment for the Low Back Pain Patients with D-Phenylalanin (DPA) Preadministration (II)
10.3777/jjsam.34.28
- VernacularTitle:D-フェニルアラニン術前投与による慢性腰下肢痛に対する鍼治療の検討 (第2報)
- Author:
Akira KAWACHI
;
Sumie TOYODA
;
Yuriko YAMADA
;
Ryuichiro KATSURAGAWA
;
Kunio KIMURA
;
Masayoshi HYODO
;
Toshikatsu KITADE
;
Eikichi HOSOYA
- Publication Type:Journal Article
- From:Journal of the Japan Society of Acupuncture and Moxibustion
1984;34(1):28-31
- CountryJapan
- Language:Japanese
-
Abstract:
We have been studying the effect of preadministration of D-phenylalanin (DPA) on acupuncture analgesia for various types of pain. DPA is thought to suppress the activity of carboxypeptidase, which discomposes endorphins. In this double-blind placebo-controled study, clinical effectiveness of acupuncture with DPA preadministration in relieving chronic low back pain was examined.
DPA (4g) or placebo (lactose: 4g) was orally administered to thirty out patients with chronic low back or lower extremity pain 30 minutes before acupuncture treatment. A half of the patients were given placebo in the first session and DPA in the second one, and the other half were given DPA firstly and placebo secondly.
The patients were asked to rate their pain after treatment in comparison with pre-treatment condition. Successful pain relief was obtained in 60% of the patients given DPA prior to acupuncture and in 33.4% of those given placebo. Although it is said that there is a great individual variation in response to acupuncture therapy, this result demonstrates that preadministration of D-phenylalanin enhances analgesic effect of acupuncture therapy.
