A Suspected Case of Heyde Syndrome with Bleeding of the Small Intestine before Aortic Valve Replacement for Severe Aortic Valve Stenosis
10.4326/jjcvs.44.346
- VernacularTitle:術前に消化管出血を合併しハイド症候群を疑った重症大動脈弁狭窄症の1例
- Author:
Takanori Kono
;
Toru Takaseya
;
Yuichiro Hirata
;
Kumiko Wada
;
Takahiro Shojima
;
Kazuyoshi Takagi
;
Koji Akasu
;
Koichi Arinaga
;
Hidetoshi Akashi
;
Hiroyuki Tanaka
- Publication Type:Journal Article
- Keywords:
Heyde syndrome;
aortic stenosis;
angiodysplasia;
von Willebrand factor
- From:Japanese Journal of Cardiovascular Surgery
2015;44(6):346-349
- CountryJapan
- Language:Japanese
-
Abstract:
The patient was a 74-year-old woman who had undergone mitral valve replacement with a mechanical valve for rheumatic mitral valve stenosis at age 60. She was scheduled for aortic valve replacement for severe aortic stenosis. However, she had significantly worsening anemia before the operation. Capsule endoscopy showed angiodysplasia with bleeding in her small intestine, which was considered the cause of the anemia. Because of progressive anemia, we tried embolization under angiography. However, there was no evidence of extravasation. Neither melena nor exacerbation of anemia was observed, and she underwent aortic valve replacement. She was discharged on postoperative day 22 without gastrointestinal bleeding. Heyde syndrome is aortic valve stenosis associated with gastrointestinal bleeding induced by von Willebrand disease and angiodysplasia in small intestine. Molecular multimeric analysis of von Willebrand factor and the existence of angiodysplasia with hemorrhage of the digestive tract are important for definitive diagnosis. Capsule endoscopy, which is a general examination, is more useful for diagnosis than molecular multimeric analysis of von Willebrand factor. Aortic valve replacement is the only therapeutic option for Heyde syndrome. It is important to decide the appropriate timing of AVR with cardiopulmonary bypass.
