Transcription of Heparansulphat interacting protein (HIP) in breast cancer tissue
- Author:
Phan Ton Hoang
- Publication Type:Journal Article
- Keywords:
breast cancer
- MeSH:
Breast Neoplasms;
Tissues
- From:Journal of Medical Research
2005;38(5):5-10
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
3 cases with cancer stage 3 were studied at K General Hospital to design heparansulfat interacting protein (HIP) primer and to assess the HIP mRNA transcription in breast cancer tissue and reference to other clinical testing methods. The method of total RNA extraction, RT - PCR for HIP cRNA and gene magnifying of HIP were used by special primers. Results: HIP transcription was up regulated in breast cancer tissue and were not found in fribroma tissue. This result is in line to those of X-ray and cytological testing. The transcription of HIP were successfully up regulated and the transcription of mRNA of HIP indicating HIP may be used as cancer marker for breast cancer diagnosis.
