HDL-Cholesterol Levels Among Rural Inhabitants
10.2185/jjrm.29.843
- VernacularTitle:農村におけるHDL-コレステロールの実態について
- Author:
Shinji Miyahara
- Publication Type:Journal Article
- From:Journal of the Japanese Association of Rural Medicine
1981;29(6):843-858
- CountryJapan
- Language:Japanese
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Abstract:
The actual state of high density lipoprotein-cholesterol levels (in part, total cholesterol ratio) among rural inhabitants in Akita Prefecture is discussed in this report based on the findings of our extensive research work from basic statistics to experiments to improve the HDL-cholesterol level.
In the basic study, we checked up on errors in measuring HDL-C levels or instrumental errors. Variations during a day (before, after eating), daily variations (five consecutive days) and seasonal variations (spring, summer, winter) were also examined. In actual fact, errors of measurement were not found, but significant errors caused by measuring instruments (precipitation method) were observed. There is no variation during a day. Daily and seasonal variations were significant.
The mean value of HDL-C levels among 386 males examined was 57.5 mg/dl±14.7, while the mean value among 359 females was 55.2 mg/dl±14.0. A normal distribution with 50-59 mg/dl as the most commonly occurring values was shown in the frequency table for both sexes. By body build, obese persons, both male and female, showed significantly lower levels than the standard value.
Geographical variations did not make any significant difference in the HDL-C level. However, the levels for those who engage in hard labor were high.
By type of disease, the group of healthy, normal persons showed higher HDL-C levels than the groups of hypertension, cerebral apoplexy, hypercholesterolemia, hypertriglyceridemia, ischemic heart disease, liver ailment and anemia. There was no significant differential between the healthy normal group and the diabetes group.
Retinal and electrocardiographical findings revealed that the normal group has higher levels than the abnormal group. It was also found that the HDL-C level has positive correlation with GOT and negative correlation with the triglyceride value.
The HDL-C level was the highest among those who drink sake and do not smoke cigarettes, and the lowest among those who smoke but do not drink sake. The difference was significant. Linkings for coffee, juice and sweets did not affect the HDL-C level.
A study was made of the changes in HDL-C levels in relation to drug administration and exercise.
For eight weeks before administration, examinations were made to find changes in the HDL-C levels of healthy normal persons. However, their mean value did not fluctuate. Eight weeks after administration, it was found that the HDL-C levels of healthy, arteriosclerotic disease and hyperliPoproteinemia groups of persons rose significantly. Diabetics and cigarette smokers showed some improvement, thought not significantly.
Exercise was rope skipping. The subjects were asked to do the light physical activity for four minutes a day over a period of four weeks. The experiment brought about significant improvements in the HDL-C levels.
