Mutagenicity of Pesticides and Their Catabolites
10.2185/jjrm.33.203
- VernacularTitle:農薬とその分解代謝物の突然変異原性について
- Author:
Masayasu Kanamaru
;
Hiroyuki Suzuki
;
Megumi Yamaguchi
;
Hideyuki Furukawa
- Publication Type:Journal Article
- From:Journal of the Japanese Association of Rural Medicine
1984;33(2):203-210
- CountryJapan
- Language:Japanese
-
Abstract:
By use of 18 varieties of pesticide and six of their breakdown products, experiments were conducted to cause mutation and reversion in S. typhimurium TA98 and TA100 within a range of 0.01ug-100 ug/plate.
The results showed that Captan had mutagenic effects on TA98 and TA100. However, when S-9 mix was added, the number of revertant colonies ceased increasing.
Ethylenthio urea caused mutations in TA98. When S-9 mix was added, revertant colonies increased about twice the number in the control. In the absense of S-9 mix, the result was the same.
