Clinical study on antimicrobial susceptibilities of Streptococcus pneumoniae isolated from respiratory specimens between 2005 and 2011
10.14442/generalist.38.345
- VernacularTitle:2005年～2011年までに呼吸器臨床検体から分離された肺炎球菌の薬剤感受性に関する検討
- Author:
Yasutaka Kuniyoshi
;
Makoto Tashiro
- Publication Type:Journal Article
- Keywords:
Streptococcus pneumoniae antimicrobial susceptibility;
antibiogram;
beta-lactam agent
- From:An Official Journal of the Japan Primary Care Association
2015;38(4):345-348
- CountryJapan
- Language:Japanese
-
Abstract:
Introduction : The purpose of this study was to investigate the changes in antimicrobial susceptibilities of Streptococcus pneumoniae (S. pneumoniae) to penicillin G (PCG), cefotaxime (CTX), and meropenem (MEPM) in specimens isolated from pediatric patients in comparison to those isolated from adults.
Methods : We retrospectively investigated laboratory records of 1062 strains of S. pneumoniae isolated between 2005 and 2011 at our hospital.
Results : In the strains isolated from children, there was no significant change in the percentage of penicillin-sensitive S. pneumoniae (PSSP). The rate of susceptibility to MEPM was significantly increased, and the rate of susceptibility to CTX was significantly reduced. The percentage of PSSP strains isolated from children was significantly lower than that in the stains isolated from adults.
Conclusion : In S. pneumoniae isolated from children, resistance to cephalosporins is increasing compared with resistance to penicillin and carbapenems. Even in the same region, strains isolated from children have a higher rate of resistance than those isolated from adults.
