Relationship Between Incidence of Pseudoaldosteronism and Daily Dose of Glycyrrhiza : Review of the Literature
- VernacularTitle:甘草の使用量と偽アルドステロン症の頻度に関する文献的調査
- Author:
Naoki MANTANI
;
Hiroshi OKA
;
Yoshiro SAHASHI
;
Ayao SUZUKI
;
Motoko AYABE
;
Mayumi SUZUKI
;
Hiroshi KAMIYAMA
;
Uruu OSADA
;
Yoko KIMURA
;
Takashi ITO
- Publication Type:Journal Article
- Keywords: glycyrrhiza; pseudoaldosteronism; incidence; dose
- From:Kampo Medicine 2015;66(3):197-202
- CountryJapan
- Language:Japanese
- Abstract: Incidence of glycyrrhiza-induced pseudoaldosteronism is not well understood. We examined relationships between pseudoaldosteronism incidence and daily glycyrrhiza dose in previous clinical studies. The incidence in patients administered glycyrrhiza 1 g/day was 1.0% (mean). The incidence with 2 g/day, 4 g/day and 6 g/day were 1.7% (mean), 3.3% and 11.1% (mean), respectively. Thus a dose-dependent trend toward pseudoaldosteronism incidence was suggested by previous literature.