Safety of Excessive Intake of Ashitaba Green Juice in Normal and Borderline Mildly Diabetic Subjects
10.1625/jcam.9.83
- VernacularTitle:健常人および境界域糖尿病者に対する明日葉青汁の過剰摂取時の安全性評価
- Author:
Hiromu OHNOGI
;
Shoko HAYAMI
;
Yoko KUDO
;
Tatsuji Enoki
- Publication Type:Journal Article
- Keywords:
Ashitaba;
green juice;
Angelica keiskei;
safety;
excessive intake
- From:Japanese Journal of Complementary and Alternative Medicine
2012;9(2):83-88
- CountryJapan
- Language:Japanese
-
Abstract:
Objective: “Ashitaba” (Angelica keiskei) is a traditional vegetable peculiar to Japan. Ashitaba contains vitamins, dietary fiber and polyphenols such as chalcones abundantly. We previously reported anti-diabetic action of Ashitaba in an animal model as well as in diabetics. In this study, we evaluated the safety of Ashitaba green juice in healthy and borderline mildly diabetic subjects.
Methods: Japanese adult subjects (n = 24) ingested Ashitaba green juice (31.5 g granulated powder) for 4 weeks. For evaluation of safety, blood chemistry analysis, hematological analysis and urinalysis were conducted.
Result: On excessive ingestion of Ashitaba green juice for 4 weeks, there were no adverse clinical changes in blood analysis and urinary analysis and no serious symptom was observed.
Conclusion: These results indicate that excessive ingestion of Ashitaba green juice is safe in healthy and borderline mildly diabetic subjects.
