Inhibitory Effect of Chaga (Inonotus obliquus) on Tumor Promotion in Two-Stage Mouse Skin Carcinogenesis
10.1625/jcam.8.29
- Author:
Ayako AKITA
;
Ken YASUKAWA
- Publication Type:Journal Article
- Keywords:
Chaga (Inonotus obliquus);
cancer prevention;
two-stage carcinogenesis
- From:Japanese Journal of Complementary and Alternative Medicine
2011;8(1):29-32
- CountryJapan
- Language:English
-
Abstract:
Chaga (the sclerotia of Inonotus obliquus) has been widely used as a folk medicine in the treatment of cancer, cardiovascular disease and diabetes in Russia, Poland, and several Baltic countries. More recently, this herb has been assessed for its cancer-preventing activity. Using a mouse model of skin cancer, oral administration of Chaga was found to inhibit tumor promotion by 12-O-tetradecanoylphorbol-13-acetate following initiation with 7,12-dimethylbenz[a]anthracene in mouse skin.
