Osteoclast-Forming Suppressive Compounds from Anoectochilus formosanus
10.1625/jcam.7.121
- Author:
Kikuko MASUDA
;
Takumi KAWAGUCHI
;
Tomoyuki KOYAMA
;
Tomio NISHIMURA
;
Hirokazu KAWAGISHI
;
Kazunaga YAZAWA
- Publication Type:Journal Article
- Keywords:
Anoectochilus formosanus osteoporosis;
osteoclast-forming suppressive substance
- From:Japanese Journal of Complementary and Alternative Medicine
2010;7(2):121-124
- CountryJapan
- Language:English
-
Abstract:
Anoectochilus formosanus, an orchidaceous plant native to Taiwan, is widely used as a folk medicine in Taiwan and other Southeast Asian countries. We attempted to isolate the bioactive principles from A. formosanus and succeeded in purifying the compounds. Two known compounds (N-cis-feruloyl tyramine and N-trans-feruloyl tyramine) were isolated and both significantly inhibited osteoclast formation, which is important in the development of osteoporosis.
