Mutagenicity Test for Hot Water Extract of Coix lacryma-jobi L. var. ma-yuen Stapf-Reverse Mutation Test, Mouse Lymphoma Assay (MLA) and Mouse Micronucleus Test
10.1625/jcam.6.157
- VernacularTitle:ハトムギ熱水抽出物の変異原性試験 ‐復帰変異試験，マウスリンフォーマ試験 （ＭＬＡ），マウス小核試験‐
- Author:
Hirotaka HAYASHI
;
Norihito ISHIBASHI
;
Mayumi OHTA
;
Takanari ARAI
;
Yuko SHIGETA
;
Jeffry M STRONG
;
Tomihisa OHTA
;
Nobutaka SUZUKI
- Publication Type:Journal Article
- Keywords:
Coix lacryma-jobi L. var. ma-yuen Stapf;
hot water extract;
reverse mutation test;
mouse lymphoma assay test;
micronucleus test
- From:Japanese Journal of Complementary and Alternative Medicine
2009;6(3):157-162
- CountryJapan
- Language:Japanese
-
Abstract:
Coix lacryma-jobi L. var. ma-yuen Stapf is a grass long been used in traditional medicine as a nourishing food and reported to possess pharmacological effects including anti-tumor, anti-obesity, anti-diabetic, etc. In order to evaluate the possible mutagenicity of the hot water extract of all parts (husks, pellicles, and astringent skin) of the food, we performed a reverse mutation test in bacteria, a mouse lymphoma assay and a mouse micronucleus test. The results of all tests were negative. It was concluded that the extract has no mutagenicity for living bodies.
