Present Status and Perspectives of Antibody Therapy against Cancer
10.1625/jcam.2.15
- VernacularTitle:抗体を利用した癌治療法の現状と新展開
- Author:
Masahide KUROKI
;
Hirotomo SHIBAGUCHI
;
Motomu KUROKI
- Publication Type:Journal Article
- Keywords:
antibody therapy;
mouse antibody;
chimeric antibody;
humanized antibody;
human antibody
- From:Japanese Journal of Complementary and Alternative Medicine
2005;2(1):15-21
- CountryJapan
- Language:Japanese
-
Abstract:
The purpose of this article is to review the current status and future perspectives of antibody therapy against cancer. Eight antibody drugs against cancer are now commercially and clinically available for treatment of cancer in the United States and two of them are also available in Japan. Current data suggest that antibodies or their genes against cancer can be used in order to increase the tumor specificity of various new immunotherapeutic or gene therapeutic approaches against cancer, thereby enhancing the tumoricidal effect of each treatment while reducing the side effects.
