Renal Sarcoidosis Monitored with Gallium Scintigraphy: Report of a Case
10.14442/general2000.1.23
- Author:
Takeshi Morimoto
;
Koji Watanabe
;
Ryotaro Kobashi
;
Kenji Kanaji
;
Tadashi Matsumura
;
Toshio Doi
- Publication Type:Journal Article
- Keywords:
sarcoidosis;
granuloma;
renal involvement;
interstitial nephritis;
hypercalcemia;
gallium scintigraphy
- From:General Medicine
2000;1(1):23-27
- CountryJapan
- Language:English
-
Abstract:
A 60-year-old male was diagnosed as having sarcoidosis four months previously because of bilateral hilar lymphadenopathy seen on a chest X-ray, uveitis, and elevation of serum angiotensin converting enzyme. In summer, the patient suffered from hypercalcemia, hypercalciuria, and renal dysfunction. Renal biopsy showed interstitial nephritis with gallium scintigraphy demonstrating high uptake in the bilateral hilum, eyes, and kidneys. Corticosteroid treatment was effective in remarkably improving the renal disorder and radiographic abnormalities.
The calcium metabolic abnormalities and the granulomatous interstitial nephritis showed a marked response to corticosteroid therapy, so that immediate administration of corticosteroid may be justified even in cases without histological evidences. Gallium scintigraphy is suggested to be useful in noninvasive examination in acute stage of sarcoidosis.
