Usefulness of Rapid Immunostaining in Intra-Operative Diagnosis of Sentinel Lymph Node Metastasis of Breast Cancer
10.2185/jjrm.63.618
- VernacularTitle:乳がんセンチネルリンパ節転移迅速診断における免疫染色併用の有用性
- Author:
Satoshi IKEDA
;
Chigusa NAGATA
;
Keiko SUZUKI
- Publication Type:Journal Article
- From:Journal of the Japanese Association of Rural Medicine
2014;63(4):618-623
- CountryJapan
- Language:Japanese
-
Abstract:
In breast cancer cases, intra-operative diagnosis of sentinel lymph node metastasis has been performed widely. It is diagnosed at present by HE staining, but more objective methods are needed. In this study using 166 examples, we compared the methods using rapid immunostaining with the genetic examination. In rapid immunostaining, we recognized metastasis using cytokeratin which was an epithelial cell marker used in the serial sections for frozen histological diagnosis. In conclusion, because metastasis could be diagnosed accurately and pathologist&rsqup;s stress would be reduced, rapid immunostaining is useful for intraoperative diagnosis.
