A Case of Schamberg Disease Successfully Treated with Keishibukuryogan Prepared at Hospital Pharmacy
10.3937/kampomed.61.924
- VernacularTitle:自家製桂枝茯苓丸が著効したＳｃｈａｍｂｅｒｇ病の１例
- Author:
Naoki OKADA
;
Masaru NATSUAKI
;
Takashi NISHIMOTO
- Publication Type:Journal Article
- Keywords:
idiopathic pigmentary purpura;
Schamberg disease;
oketsu;
keishibukuryogan
- From:Kampo Medicine
2010;61(7):924-929
- CountryJapan
- Language:Japanese
-
Abstract:
Schamberg disease is a subtype of idiopathic pigmentary purpura, which manifests with petechiae. It is assumed to be caused by venous microcirculatory disturbance, or an immunological and allergic mechanism. We report a 55-year-old Japanese male with Schamberg disease successfully treated with keishibukuryogan prepared at a hospital pharmacy. The patient had purpuric eruptions in his both lower legs at first, and brownish pigmentation enlarged with purpura. A dermatologist had diagnosed this, from the clinical findings, as Schamberg disease. We administered keishibukuryogan to the patient because his pathological condition was considered as oketsu. In order to improve effectiveness, keishibukuryogan was manufactured according to our own modification. The eruptions have reduced gradually, and about four months later, have mostly resolved. A Kampo therapy utilizing unseiin has been reported to be effective against idiopathic pigmentary purpura in previous studies. We suggest that a Kampo treatment with keishibukuryogan seems to be effective against idiopathic pigmentary purpura through improvements of microcirculation and inflammation.
