Two Cases of Autoimmune Pancreatitis-Induced Obstructive Jaundice Treated with Inchinkoto
10.3937/kampomed.65.202
- VernacularTitle:自己免疫性膵炎による閉塞性黄疸に茵蔯蒿湯を使用した2症例
- Author:
Hideyuki KITAHARA
;
Tatsuya NOGAMI
;
Hiroki MISAWA
;
Sayuri ARAI
;
Shigeru EBISAWA
;
Hidetoshi WATARI
;
Makoto FUJIMOTO
;
Hiroshi FUJINAGA
;
Hiroaki HIKIAMI
;
Kozo TAKAHASHI
;
Naotoshi SHIBAHARA
;
Yutaka SHIMADA
- Publication Type:Journal Article
- Keywords:
inchinkoto;
obstructive jaundice;
autoimmune pancreatitis;
IgG 4-related disease
- From:Kampo Medicine
2014;65(3):202-209
- CountryJapan
- Language:Japanese
-
Abstract:
We report two cases of inchinkoto treatment for obstructive jaundice via autoimmune pancreatitis (AIP). Case 1 : A 38-year-old male. After completion of treatment for Mikulicz disease, obstructive jaundice developed. A diagnosis of AIP was based on a high IgG 4 blood level and image views. T-Bil stayed above 20 mg/dl and there was no improvement by oral administration of prednisolone (PSL), ursodeoxycholic acid, or bilirubin adsorption therapy. Upon inchinkoto administration, T-Bil promptly fell to 3 mg/dL. Case 2 : A 77-year-old male. He suffered from itching and constipation, and blood data showed a pattern of obstructive jaundice. Image views suggested AIP, but a duodenal papillary biopsy could not provide a definitive diagnosis. Inchinkoto was administered, and the itching and constipation had mostly disappeared within 1 week. However, these symptoms recurred after one month. A definitive diagnosis of AIP was then reached based on a pancreas biopsy, and a PSL regimen was initiated. From these two cases, we consider that inchinkoto is useful for improving the symptoms of obstructive jaundice induced by AIP.
