A Case of Recurrent Fever Successfully Treated with Yokukansan
10.3937/kampomed.65.191
- VernacularTitle:反復性発熱に抑肝散が奏効した一例
- Author:
Yukari GONO
;
Hiromitsu HOTTA
;
Toshiyuki OKUTOMI
;
Tetsuro OIKAWA
;
Toshihiko HANAWA
- Publication Type:Journal Article
- Keywords:
recurrent fever;
fever of unknown origin (FUO);
periodic fever syndrome;
yokukansan
- From:Kampo Medicine
2014;65(3):191-196
- CountryJapan
- Language:Japanese
-
Abstract:
The patient was a 14 year-old female. She had been hospitalized repeatedly since infancy for suspected tonsillitis. During this time, she experienced high fever for about a week once a month. In her school years, she often had a recurrent fever with cervical adenitis, with only a mild inflammatory reaction. We diagnosed her symptom as one of a periodic fever syndrome, triggered by the frequent administered antipyretic drugs for fevers of unknown origin (FUO). We also suspected that there was liver tension, based on her abdominal and back examination, and we prescribed yokukansan. After a 3-month course of yokukansan, she no longer experienced these fevers. Most case reports of FUO describe the use of bupleurum root drugs and tonic formulas as treatment. Although yokukansan has traditionally been used for FUO in older texts, to our knowledge, there are no reports on such use clinically. In the present patient's case, the yokukansan may have reduced or eliminated some type of trigger for the fevers, or it may have affected the regulation of cytokines.
