Lifestyle intervention-induced increase in light physical activity may improve insulin resistance in overweight and obese men
10.7600/jspfsm.63.415
- VernacularTitle:肥満男性における生活習慣介入に伴う低強度身体活動時間の増加はインスリン抵抗性を改善させる
- Author:
Takehiko Tsujimoto
;
Rina So
;
Bokun Kim
;
Chiaki Kato
;
Nami Kobayashi
;
Shun Suzuki
;
Kiyoji Tanaka
- Publication Type:Journal Article
- Keywords:
physical activity;
lifestyle intervention;
insulin resistance
- From:Japanese Journal of Physical Fitness and Sports Medicine
2014;63(4):415-423
- CountryJapan
- Language:English
-
Abstract:
Moderate to vigorous physical activity is associated with improving insulin resistance in overweight and obese adults. However, effect of light physical activity on insulin resistance remains to be fully elucidated. The purpose of this study was to investigate the effect of light physical activity on insulin resistance in overweight and obese men. Thirty-seven overweight and obese middle-aged men (28.9 ± 1.8 kg/m2, 51.0 ± 8.8 years) participated in this study. They took part in the lifestyle intervention (calorie restricted diet and exercise) for 12 weeks. Anthropometric parameters, fasting glucose, HbA1c, fasting insulin, and HOMA-IR were assessed at baseline and post intervention. Physical activity was objectively measured using a triaxial accelerometer at baseline and during intervention. Light physical activity (+17.7 min/day) and moderate-vigorous physical activity (+33.2 min/day) increased significantly, while body weight (-12.4 kg), fasting glucose (-9.5 mg/ml), fasting insulin (-4.2 μU/ml), and HOMA-IR (-1.1) decreased significantly. The change in light physical activity from baseline to during intervention were inversely related to change in fasting insulin (r = 0.18, P = 0.02) and change in HOMA-IR (r = -0.16, P = 0.03), after adjustment for several confounders. These results suggest that an increase of light physical activity improves insulin resistance in overweight and obese men.
