Oral Administration of the Potato Peel Extract Affects Cytokine Production in Murine Peyer’s Patch Cells
10.1625/jcam.11.107
- VernacularTitle:じゃがいも皮抽出物の経口投与によるマウスパイエル板細胞のサイトカイン産生への影響
- Author:
Mari SUTO
;
Suguru KATO
;
Megumi IRISAWA
;
Megumi ICHISAWA
;
Katsuyuki ISHIHARA
;
Rui SAKUMA
;
Shinji FUSHIYA
;
Fumihide TAKANO
- Publication Type:Journal Article
- Keywords:
Potato peel;
Peyer’s patch;
cytokine
- From:Japanese Journal of Complementary and Alternative Medicine
2014;11(2):107-110
- CountryJapan
- Language:Japanese
-
Abstract:
We investigated the effects of an ethanol extract of potato peel on T helper cytokines production in cultured murine Peyer’s patch cells ex vivo. Oral administration of the 70% ethanol extract at 100 mg/kg/day significantly enhanced the production of the Th1 cytokine IL-2 in response to concanavalin A. A decrease in the production of the Th2 cytokine IL-4 and the Th17 cytokine IL-17 was observed. The production of the Treg cytokine IL-10 was not affected. These results suggest that the potato peel extract stimulates Th1 immune response.
