Detection of High Risk Type HPV by Means of Clinichiptm in Patients with Cervical Dysplasia
10.2185/jjrm.63.29
- VernacularTitle:子宮頚部異形成患者に対するクリニチップ™を用いたHPV検出
- Author:
Satoshi IKEDA
;
Chigusa NAGATA
;
Koji SHIMABUKURO
;
Keiko SUZUKI
- Publication Type:Journal Article
- From:Journal of the Japanese Association of Rural Medicine
2014;63(1):29-34
- CountryJapan
- Language:Japanese
-
Abstract:
It is known that uterine cervical cancer is caused by persistent infection with high-risk type of HPV (human papilloma virus). We have run HPV genotyping tests on patients since November, 2011. In 111 cases so far examined, HPV types 16, 52 and 58 were detected with high frequency, but type 18 was with low frequency. This trend was comparable to nationwide tendency. Type 52, 56 and 58 were detected from the patients of advanced age frequently. There weredifferences in HPV infection rate between cytology-negative cases and positive cases, but there was not the difference in HPV typing by cytology-negative and positive patients. Furthermore, it was made clear that the superinfection of HPV who significantly related to the development of tumor. In the cytology negative patients who were followed up because of dysplasia, there are many who are negative for high risk HPV. Therefore, HPV genotyping examination may help physicians determine the relative priority for treatment.