Therapeutic Strategy for Parkinson's Disease
10.2490/jjrmc.51.700
- VernacularTitle:パーキンソン病の総合的治療方針
- Author:
Taku HATANO
;
Akito HAYASHI
;
Nobutaka HATTORI
- Publication Type:Journal Article
- Keywords:
Parkinson's disease;
levodopa;
rehabilitation;
neuroplasticity
- From:The Japanese Journal of Rehabilitation Medicine
2014;51(11):700-704
- CountryJapan
- Language:Japanese
-
Abstract:
Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease, characterized by increasingly morbid motor dysfunction with advancing age. Recently, various antiparkinsonian agents and surgical intervention have been developed that, when used in combination, greatly promote sustained improvements in activities of daily living, leading to the establishment of a treatment algorithm. However, since all of these interventions are symptomatic therapies, it is difficult to resolve motor dysfunction completely. Recent evidence has revealed that exercise might enhance neuroplasticity and improve motor and cognitive behavioral impairment in PD. In this article, we reviewed recent therapeutic strategies for PD.
