Syncope Caused by Portopulmonary Hypertension : A Case Report
- Author:
Toshikazu Abe
;
Yasuharu Tokuda
;
Takako Kitahara
;
Shunsuke Sakai
;
Masahiro Toyama
;
Shigeyuki Watanabe
- Publication Type:Journal Article
- Keywords:
portopulmonary hypertension;
syncope;
ambrisentan;
liver cirrhosis
- From:General Medicine
2012;13(2):113-116
- CountryJapan
- Language:English
-
Abstract:
Syncope is a common chief complaint in emergency departments, and although causes in most patients with syncope are benign, some patients have a serious disease. Here we report a 50-year-old patient with facial trauma who had past history of alcoholic liver cirrhosis. He fell down by syncope due to portopulmonary hypertension (PPHTN) accompanied by portal hypertension. Oral ambrisentan, a potent ETA-selective receptor, 2.5 mg once a day was initiated. His ECG and the results of cardiac catheterization showed improvement in hemodynamic abnormality after the treatment. Also, the patient had no significant symptoms, including syncope, for nine months after receiving ambrisentan.
