Effect of tramadol on cancer pain in a patient with advanced endometrial carcinoma and myasthenia gravis: a case report
10.2512/jspm.8.570
- VernacularTitle:重症筋無力症を有するがん疼痛患者に対するトラマドールの導入
- Author:
Yoshihiro Yamamoto
;
Maki Todo
;
Kikuyo Nishida
;
Keita Iwasaki
;
Chiharu Suzuki
;
Miki Kondo
;
Shoko Kinoshita
;
Kazuyo Kanbara
;
Hiromitsu Yabushita
;
Akihiko Wakatsuki
;
Katsuhiko Matsuura
;
Mari Nishihara
;
Kenichi Arai
- Publication Type:Journal Article
- Keywords:
myasthenia gravis;
tramadol;
anticholinergic effect;
cancer pain
- From:Palliative Care Research
2013;8(2):570-574
- CountryJapan
- Language:Japanese
-
Abstract:
Introduction: Tramadol (TRM) has been included as a weak opioid at the second step of the WHO analgesic ladder and has been widely used in palliative medicine. Here we report a case of amelioration of cancer pain by TRM therapy in a female patient with myasthenia gravis (MG). Case:The patient was a 70’s woman who was diagnosed with advanced endometrial carcinoma and suffered from chest pain caused by chest metastasis. 25 mg of a TRM capsule was orally administered three times a day. The dose was increased to 50 mg twice a day. It was resulted in sound pain relief with transient muscle weakness but without a myasthenic crisis.
