Lymphoscintigraphy of Eyeball and Ocular Adnexal Malignant Tumors.
- Author:
Chan Soo PARK
1
;
Jun Hyuk SON
;
Wha Sun CHUNG
;
Ihn Ho CHO
Author Information
1. Department of Ophthalmology, Yeungnam University College of Medicine, Daegu, Korea. chungwha@med.yu.ac.kr
- Publication Type:Original Article
- Keywords:
Eyeball and ocular adnexal malignant tumors;
Lymphoscintigraphy;
Sentinel lymph node
- MeSH:
Antimony;
Biopsy;
Colloids;
Drainage;
Gamma Cameras;
Humans;
Lymph Nodes;
Lymphoscintigraphy*;
Melanoma;
Neoplasm Metastasis;
Sebaceous Glands
- From:Journal of the Korean Ophthalmological Society
2004;45(6):893-898
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the usefulness of preoperative or postoperative lymphoscintigraphy for the identification of lymphatic drainage and sentinel lymph node in patients with eyeball and ocular adnexal malignant tumors. METHODS: Lymphoscintigraphy was performed preoperatively or postoperatively in 5 patients with biopsy proven primary eyeball or ocular adnexal malignant tumors. Patients underwent lymphoscintigraphy with 500 micro Ci of technetium-99m antimony trisulfide colloid in a volume of 0.1 ml. We injected intradermally either the outer 1/3 of the upper or lower lid, or the inner 1/3 of the upper or lower lid. Images were taken by Gamma camera and we checked lymphatic drainage and sentinel lymph nodes. RESULTS: Two patients with conjunctival malignant melanoma showed normal lymphatic drainage, but the other two patients had lymphatic drainage to the parotid and submandibular chain, and sentinel lymph nodes were noted as the parotid lymph node and the submandibular lymph node. The patients with sebaceous gland carcinoma injected in the outer 1/3 of the upper lid had submandibular lymphatic chain and the sentinel lymph node proved to be the submandibular lymph node. CONCLUSIONS: Lymphoscintigraphy demonstrated the lymphatic drainage system and successfully identified the sentinel lymph nodes. This should prove to be very helpful to evaluate metastasis of the eyeball and ocular adnexal malignant tumors by selective lymph node biopsy and to decide the degree of surgery.
