Clinical efficacy of the external preparation Metronidazole in the treatment of malodor associated with advanced and recurrent breast cancer
10.2512/jspm.2.218
- VernacularTitle:進行再発乳がん患者のがん性悪臭に対するメトロニダゾール外用剤の有用性に関する検討
- Author:
Hiromi Shinano
;
Kazuhiro Watanabe
;
Seigo Nakamura
;
Yoko Tamahashi
;
Masao Tsuchiya
;
Junko Kizu
;
Tadao Inoue
- Publication Type:Journal Article
- Keywords:
metronidazole;
breast cancer;
cancerous malodor;
hospital preparation
- From:Palliative Care Research
2007;2(2):218-222
- CountryJapan
- Language:Japanese
-
Abstract:
The external preparation Metronidazole (MTZ) is reported to be useful in controlling the malodor associated with advanced and recurrent breast cancer patients. We prepared two different MTZ external preparations, a 1% MTZ Hydrophilic Ointment and a 0.8% MTZ Carbopol Gel. These preparations were then used to control malodor associated with breast cancer and the results were clinically evaluated. Malodor disappeared within 1 week of administration of either preparation and no adverse reactions were observed. These MTZ external preparations were thus found to be useful in the elimination of malodor as part of the treatment of those patients with advanced and recurrent breast cancer.
