Drug Use in Renal Insufficiency, Drug-induced Nephropathy.
10.2185/jjrm.51.63
- VernacularTitle:腎障害時の薬剤の使い方，薬剤による腎障害 実地医家が用いる薬剤を中心に
- Author:
Tatsuo SHIIGAI
;
Kazuko OHGUSHI
;
Yasushi SAKURAI
;
Hiromi NAITOU
- Publication Type:Journal Article
- From:Journal of the Japanese Association of Rural Medicine
2002;51(2):63-67
- CountryJapan
- Language:Japanese
-
Abstract:
We should decide the dose in renal insufficiency according to an attachment document, estimated by Cockroft-Gault's formula. It is better not to decide the dose only byexcretion route. In addition, we should not administer the nephrotoxic drugs, especially NSAIDs, to renal insufficiency.
Also, it is necessary to pay enough attention to the overdose of drugs, which do not cause renal toxicity but cause dangerous side effects to the central nervous system.
Many attachment documents have a lot of lacks in the mention for renal insufficiency and need to be improved.
