A Case of Churg-Strauss Syndrome (Allergic Granulomatous Angiitis) with Severe Heart Failure Treated by Steroid Pulse Therapy.

VernacularTitle:重症心不全をきたしたステロイドパルス療法を施行したＣｈｕｒｇ‐Ｓｔｒａｕｓｓ症候群（アレルギー性肉芽腫性血管炎）の１例
Author: Satoru TAKEDA ; Toshiaki TAKAHASHI ; Kaori OHMORI ; Kohei FUKAHORI ; Masayuki YOSHIDA ; Koki SAITO ; Etsuko FUSHIMI ; Nobuyo SEKIGUCHI ; Toru TAKAHASHI ; Keiji KIMURA ; Masato HAYASHI ; Masahiro SAITO
Publication Type:Journal Article
From:Journal of the Japanese Association of Rural Medicine 2002;51(2):127-133
CountryJapan
Language:Japanese
Abstract: A19-year-old man was admitted to the hospital because of severe congestive heart failure on 7 April 2000. In the previous year his case had been diagnosed as Churg-Strauss syndrome (allergic granulomatous angiitis, AGA) with bronchial asthma and mononeuritis multiplex. Echocardiography revealed the dilatation of the left ventricle (LVDd 74 mm) and impaired left ventricular systolic function (LVEF 20%). On the 21st hospital day, the irregularity of peripheral branches of left and right coronary arteries was detected by coronary arteriography. Right ventricular endomyocardial biopsy yielded little fibrosis and no infiltration of eosinophil. Although all the laboratory tests showed lower activity of AGA, steroid pulse therapy was tried and the use of steroids was tapered at intervals of two weeks. Left ventricular function was slowly improved (LVDd 60 mm, LVEF 36%). He was discharged on foot on the 71st hospital day.