Evaluation of Changes in Activity of Serum Enzymes(AST,ALT,.GAMMA.-GT) with Age and Gender Differences.

VernacularTitle:血清酵素活性（ＡＳＴ，ＡＬＴ，γ‐ＧＴ）の性差，加齢による影響の比較検討
Author: Yukio ESUMI ; Kohtarou TOMIMURA ; Yasuhiko FUKADA
Publication Type:Journal Article
From:Journal of the Japanese Association of Rural Medicine 2001;49(5):750-757
CountryJapan
Language:Japanese
Abstract: The purpose of this study was to elucidate effects of aging on the activity of serum enzymes (AST, ALT, γ-GT). For this purpose, we used the results of the mass health screening tests run on a total of 14, 738 residents in Shimane Prefecture. We selected 1, 814 samples by excluding those 6 test items.
AST levels increased in both sexes with age, and peaked in the age group of 70s (29 IU/1) in men, while in women the age groups of 70s and, 80s (26 IU/1). ALT levels increased in men in their 50s (34 IU/1) and decreased gradually in their 60s, whereas in women levels did not clearly change.
γ-GT levels peaked in men in the age group of 40s (50 IU/1), whereas in women levels did not clearly change. We compared the γ-GT levels of drinkers and non-drinkers. In the drinkers, the γ-GT levels were higher than the non-drinkers in men, but in women the levels were not clearly change.