A Clinical and Epidemiological Review on Chronic Pesticide Poisoning (Disorders). 2. Disorders in Organs.
10.2185/jjrm.44.65
- VernacularTitle:農薬慢性中毒（障害）の臨床的・疫学的考察 その２． 各臓器障害
- Author:
Shosui MATSUSHIMA
- Publication Type:Journal Article
- From:Journal of the Japanese Association of Rural Medicine
1995;44(2):65-73
- CountryJapan
- Language:Japanese
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Abstract:
Of all chronic pesticide poisoning (disorders), this is an attempt to review pulmo-bronchial disorders, hepatic disorders, stomach disorders, blood and hematopoietic disorders, hypertension and vascular disorders, dysbolism and immunological disorders in a clinical and epidemiological perspective.
The pulmo-bronchial disorders consist mostly of those with pneumonic episodes and chronic progressive lung fibrosis. Then there were asthma, chronic bronchitis and degenerated hepatic functions, among others. The prevalence of hepatic disorders was high among persons exposed to pesticides, and they were caused by organochlorine and TCDD. Then there were cases with hepatic cirrhosis because of a continued intake of arsenic, a residue in the wine. When it comes to stomach disorders, some were caused by a sustained exposure to organophosphate and sustained intakes from vegetables. In regard to blood and hematopoietic disorders, many cases with apalastic anemia caused by PCP and other blood diseases were observed. As for vascular disorders, cases with arteriosclerotic episodes by paraquat, whereas cases with porphyria by HCB and hyperlipemia by organochlorine. Then there were cases with immunological abnormalities by organochlorine, organophosphate and carbamate.
As many pesticides are mucocutaneously stimulative and allergic in addition to their own toxicity, there is a need to give thought to their compound effects when it comes to disorders to human bodies.
