Stroke onset and heart disease.

VernacularTitle:心疾患と脳卒中発症について
Author: Hideomi FUJIWARA
Publication Type:Journal Article
From:Journal of the Japanese Association of Rural Medicine 1988;36(5):1085-1089
CountryJapan
Language:Japanese
Abstract: Generally, valvular heart disease, pacemaker implantation and atrial fibrillation are considered to have some relationship to the onset of stroke, because of their tendency for intracardiac thrombus formation. But the factors which influence the stroke onset have not be clarified precisely. We examined underlying heart disease in patients with cerebral infarction whose clinical courses could be known clearly. Heart diseases were complicated in 11 cases of 25 patients with stroke. Tcese 11 cases consisted with myopathy (3 cases), valvular heart disesase (3 cases), pacemaker implantation (2 cases) and others (3 cases). In 14 cases with intracardiac thrombus, only 3 cases were revealed to become stroke. In 122 pacemaker implanted patients, 6 cases were died with stroke. Risk factors and genetic analysis of lipids were evaluated in both cerebral infarction and myocardial infarction. Although the rate of complication with hypertension was significantly higher in both cerebral infarction and myocardial infarction than in normal controls, the rate of complication with hyperlipidemia was lower in cerebral infarction. As the some specific genotypes of Apo-E were seen in myocardial infarction, they were never seen in cerebral infarction.