Prediction of ischemic cerebrovascular disorders.
10.2185/jjrm.36.1057
- VernacularTitle:虚血性脳血管障害の近接予知
- Author:
Masato HAYASHI
;
Ken-ichi HOSOYA
- Publication Type:Journal Article
- From:Journal of the Japanese Association of Rural Medicine
1988;36(5):1057-1064
- CountryJapan
- Language:Japanese
-
Abstract:
It has been reported by many workers that the patients with atrial fibrillation have risk factors that give rise to cerebral infarction. Nonetheless, no report has been made on whether or not there can be a difference in the development of ischemic cerebrovascular disorders, depending on the actual condition at the onset of atrial fibrillation, particularly a varying degree of ventricular pause and heart rate, etc.
Investigations were made on 318 patients with continuous atrial fibrillation and 114 with paroximal atrial fibrillation in a total of 432 patients, ranging in age from 22 to 89 years in a ratio of 2: 1 between male and female with a mean of 65.1±11.2 years, who were included in the current study.
The results have proved to be worthwhile when ventricular pause was studied by Holter's ECG. When ischemic cerebrovascular disorders were observed at varying intervals longer than 2.5, 3 and 4 seconds, a significant difference was noted between the intervals longer than 2.5 and 4 seconds in the incidence of ischemic cerebrovascular disorders (p<0.05). Lone atrial fibrillation showed a similar tendency in this aspect, regardless of the presence or absence of basic diseases.
The duration of ventricular pause remained unchanged in the therapy combined with digitalis, but significantly extended when Ca-antagonist, and Beta-blocker were used. Thus, it may be important to be carafau in the selection of medications.
