Effects of 38.DEG.C. Bathing for 30 min on Hemostatic Function and Autonomic Nervous Function in Patients with Cerebral Infarction.
- VernacularTitle:３８℃，３０分間の入浴が止血機能と自律神経に与える効果 脳梗塞既往者を対象にして
- Author:
Yumi KATOH
;
Toshiaki YOSHIDA
;
Mariko AIHARA
;
Masakazu NITTA
;
Hiroyuki SHIONO
;
Junichi SAKAI
;
Tadashi OKADA
;
Isamu SUGIE
;
Nariaki IIJIMA
- Publication Type:Journal Article
- Keywords:
tissue plasminogen activator (t-PA);
plasminogen activator inhibitor-1 (PAI-1);
cerebral infarction;
bathing;
fibrinolytic activity
- From:The Journal of The Japanese Society of Balneology, Climatology and Physical Medicine
2001;64(2):93-102
- CountryJapan
- Language:Japanese
-
Abstract:
Effects of 38°C 30-minute bathing on hemostatic function and autonomic nervous function were studied in 15 48-to-72-year-old patients with cerebral infarction. Blood samples were collected three times: immediately before the bathing, at the end of 30 minutes of bathing, and 30 minutes after the bathing. Hematocrit values and fibrinogen concentrations decreased during bathing and returned to the pre-bathing levels 30 minutes after bathing. This indicates that bathing caused hemodilution due to the fluid shift. During bathing, noradrenaline decreased at a rate significantly higher than that of hemodilution while the sympathetic nervous function, which was evaluated by spectral analysis of sequential variation in arterial blood pressure, was not suppressed. The autonomic nervous system seemed to be inactive in these patients. Coagulation time (PT and APTT) and platelet factor (β-TG and PF4) showed few changes. In the fibrinolytic system, however, tissue plasminogen activator (t-PA) antigen levels increased and plasminogen activator inhibitor type-1 (PAI-1) levels decreased after 30 minutes of bathing. This suggests that fibrinolytic activity was enhanced by 38°C bathing for 30 minutes. Thus, subthermal bathing with comfort may be useful in preventing cerebral infarction.
