Variation of Cell Populations Taking Charge of Immunity in Human Peripheral Blood Following Hot Spring Bathing. Qualitative Discussion.
- VernacularTitle:短期温泉浴と末梢血液中免疫担当細胞への影響 質的検討
- Author:
Hideo MATSUNO
;
Xiu-Xia WANG
;
Wenhan WAND
;
Kenichiro MATSUI
;
Shoko OHKAWA
;
Tohru SUGIYAMA
;
Hiroyuki KOHNO
;
Shoji SHIMIZU
;
Jin-Ear LAI
;
Masao YAMAGUCHI
;
Nobuo YAMAGUCHI
- Publication Type:Journal Article
- Keywords:
Hot spring bathing;
Immunity;
Cytokine containing cell
- From:The Journal of The Japanese Society of Balneology, Climatology and Physical Medicine
1999;62(3):135-140
- CountryJapan
- Language:Japanese
-
Abstract:
We have simultaneously proved that cell populations taking charge of immunity in human peripheral blood can be regulated quantitatively by hot spring bathing. Now, we investigated the effect of hot spring bathing qualitatively on cytokine production by lymphocyte cell in human peripheral blood estimating by cytokine containing cell by FACScan. We found a significant increase in IFN-γ containing cells after hot spring bathing and an increase in IL-4 with no statistical significance after hot spring bathing. In addition, we found significant negative relationship between the level of IFN-γ, IL-4 and IL-1β before hot spring bathing and the ratio of cytokine that increased in variation after hot spring bathing. Namely, after hot spring bathing, there was a decrease of cytokine producing cells in subjects who had higher level before hot spring bathing. But an increase in subjects who had lower level before hot spring bathing, the trend was concentrated toward average levels in the cytokine production by lymphocyte in peripheral blood. So we suggest that hot spring bathing can promote acquired immunity to make it possible more suitable as immune reaction.
