The Effect of Bathing with NY-008 on Skin Temperature.
- VernacularTitle:ＮＹ‐００８含有温水浴が皮膚表面温度に及ぼす影響
- Author:
Nobutaka TAGUCHI
;
Futoshi OGITA
;
Hirotaka SATO
;
Hidenori YOROZU
- Publication Type:Journal Article
- Keywords:
NY-008 bathing;
Skin temperature;
Skin blood flow;
Mean blood pressure
- From:The Journal of The Japanese Society of Balneology, Climatology and Physical Medicine
1995;58(2):101-108
- CountryJapan
- Language:Japanese
-
Abstract:
The effect of bathing with NY-008 (3-octylphthalide, a newly synthesized vasodilative compound) on skin temperature was examined. The subjects were 28 healthy male adults (22±4 years old). The group bathed for 10min in 40°C water containing 3ppm of NY-008. On alternate days, the group bathed similarly but without NY-008 (control bathing). Skin temperature (Ts), blood pressure, and heart rate (HR) were then measured in a room in which the ambient temperature was maintained at 24°C and relative humidity at 60%. To eliminate any effect of diurnal fluctuations in skin temperature, each subject bathed at the same hour each day. Measurements were performed in random order by the double-blind method. The mean values of Ts after bathing were slightly higher after NY-008 bathing than after control bathing, and a significant difference was noted 10min after bathing (p<0.01). There was no significant difference in systolic blood pressure between NY-008 bathing and control bathing. Diastolic blood pressure was slightly lower after NY-008 bathing. Mean blood pressure, measured 5 min after bathing, was significantly lower after NY-008 bathing than after control bathing (p<0.05). No significant difference was found in HR. These findings suggest that NY-008 bathing increases skin blood flow through vasodilation of skin vessels and lower peripheral resistance, and may have longer lasting warming effects than ordinary bathing.
