Hepatoprotective and Anti-cirrhotic Effects of Hypericum patulum Thumb. ex Murr
- Author:
Nguyen Quoc Thuc
- Publication Type:Journal Article
- Keywords:
Hypericum patulum Thumb. ex Murr.
- MeSH:
Plants;
Hepatitis, Chronic;
Plants, Medicinal;
liver;
drugs
- From:Journal of Medicinal Materials - Hanoi
2003;8(5):152-156
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Water extract of Hypericum patulum Thumb. ex Murr. has been proved to possess the effects of decreasing GPT hepatoyeast and bilirubin, inhibiting anti-cirrhotic, decreasing the amount of colagen by 26.4%, antioxidant, amount of MDA of the treated mice decreased by 22.62%. Water extract of Hypericum patulum Thumb. ex Murr. has chronic anti - inflammatory effect on the model causing experimental granuloma, reducing the mass of tumor by 30.22%. In addition, water extract of Hypericum patulum Thumb. ex Murr. has clearly choleretic activities, increasing the number of producing bile by 78.55% as compared with physiological control group. Water extract of Hypericum patulum Thumb. ex Murr. has promising for a medicament for chronic hepatitis activity.
