The effect of endurance training on the pancreatic enzyme activity in aged rats.
- VernacularTitle:老齢ラットのすい酵素活性に及ぼす持久的運動習慣の影響
- Author:
KUMIKO MINATO
;
HISASHI NAITO
- Publication Type:Journal Article
- Keywords:
aging;
pancreatic enzyme;
amylase;
endurance training
- From:Japanese Journal of Physical Fitness and Sports Medicine
1999;48(2):245-250
- CountryJapan
- Language:Japanese
-
Abstract:
The purpose of the present study was to investigate the effect of endurance running training on pancreatic enzyme activity in aged rats. Young (Y ; age, 12 weeks) and old (O ; age, 100 weeks) female Fischer 344 rats were divided into control (YC ; n = 6, OC ; n = 4) and trained (YT ; n = 6, OT ; n=7) groups respectively. Rats in the YC and OC groups were kept sedentary. Rats in the YT and OT groups ran up a 15% gradient treadmill for 60 min a day (final speed, YT : 32 m ⋅min-1, OT 22 m⋅min-1), 5 days a week. After 10 weeks, the pancreas was excised and weighed. Protein content, amylase and lipase activities in pancreatic tissue were measured. Pancreatic wet weight, protein content, and enzymes (amylase and lipase) activity in the OC group were significantly lower than in the YC group. However, these parameters in the OT group were significantly higher than in the OC group. These results suggest that endurance training may restore the age-related decrease of pancreatic enzyme synthesis and storage.
