Studies on Pharmacological Effects of Crinum asiaticum L
- Author:
Nguyen Kim Phuong
- Publication Type:Journal Article
- Keywords:
Crinum asiaticum L.
- MeSH:
Plants;
Plants, Medicinal;
Biochemistry;
drugs
- From:Journal of Medicinal Materials - Hanoi
2003;8(5):149-152
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The experiment was studied on the male, young and strong rats of the body weight of 80-100gr. Rats were divided into 3 groups, 9 rats in each group. Alcoholic extract and alkaloid fraction of the leaves of Crinum asiaticum L. were subjected to pharmacological studies. The results showed that:
1. LD50 of the alcoholic extract is 22.75 g/kg p.o. in mice on dry basis.
2. Subchronic anti-inflammatory effect of the alcoholic extract is stronger than that of the alkaloid fraction.
3. Both alcoholic extract and alkaloid fraction inhibit the prostatic hypertrophy induced experimentally by testosterone.
