Decrease of pulsatile gonadotropin secretion in female athletes.
- Author:
NOBORU MESAKI
;
JUNICHI SASAKI
;
YUICHI NABESHIMA
;
SATOSHI SOHDA
;
MASAKI MOTOBU
;
KATSUMI ASANO
;
MASASUKE EDA
- Publication Type:Journal Article
- Keywords:
Female athlete;
Gonadotropin;
Pulsatile secretion;
Hypothalamic insufficiency
- From:Japanese Journal of Physical Fitness and Sports Medicine
1991;40(4):365-371
- CountryJapan
- Language:English
-
Abstract:
Ten athletic women (5 normal ovulatory cycles, 5 short luteal phases) and 6 non-athletic women with normal ovulatory cycles were subjected to an investigation of episodic gonadotropin secretion. In the middle follicular phase, blood samples were obtained via an indwelling venous catheter every 15 minutes for 4 hours.
Mean levels of gonadotropins in both athletic groups were lower (p<0.001) than in the control group. LH pulse frequencies in the short luteal group were significantly lower than in the control group (p<0.001) . LH pulse amplitudes were similar in all groups. FSH dynamics were the same as those for LH.
In athletic women, low mean levels and infrequent episodic secretion of gonadotropins were obvious. These data suggest that strenuous athletic activity may cause hypothalamic-pituitary insufficiency, especially that of hypothalamic origin.
