Effects of Morinda sp. on Liver Injury Induced by Paracetamol in Rats
- Author:
Dao Van Phan
- Publication Type:Journal Article
- Keywords:
Morinda sp.
- MeSH:
Liver;
Acetaminophen;
Biochemistry;
animal experimentation
- From:Journal of Medicinal Materials - Hanoi
2003;8(5):139-142
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Effects of aqueous extracts from the root of Morinda sp. were studied on liver injury induced by a high dose of paracetamol (acetaminophen) in rats. The results showed that the extract had a hepatoprotective effect at a dose of 10g/kg of body weight. The effect was similar to that of silymarin at a dose of 25mg/kg of body weight in terms of AST, ALT activities, total serum cholesterol and protein concentrations as well as macro-and microscopic histological studies of the liver.
