Cholesterol metabolism in rat after two intensities of treadmill exercise training.
- VernacularTitle:ラット肝コレステロール代謝に及ぼすトレーニング強度の影響
- Author:
TAKASHI ABE
;
TERUFUMI SAKAMOTO
;
HIDEO HATTA
;
YOSHIHIRO ITAI
;
TOSHIO ASAMI
;
TOKUHIKO HIGASHI
;
KOICHI HIROTA
- Publication Type:Journal Article
- Keywords:
exercise;
training intensity;
HMG-CoA reductase;
cholesterol
- From:Japanese Journal of Physical Fitness and Sports Medicine
1987;36(5):279-286
- CountryJapan
- Language:Japanese
-
Abstract:
In this study, we investigated the effect of exercise training on serum and liver chblesterol levels and on biosynthesis of liver cholesterol in rats. The training was carried out at low [Low-Ex, 60% max O2 consumption (VO2) ] and high (High-Ex, 75% max VO2) intensities for 16 weeks. The energy expenditure was adjusted to be equivalent. The succinate dehydrogenase activities of gastrocnemius muscle in the Low-Ex group and High-Ex group were higher than that of control, 36% and 109% (p<0.05) respectively. The levels of total and high density lipoprotein cholesterol in serum were 14-26% lower than those of control, but no difference was detected between the trained groups. The activity of HMG-CoA reductase in liver microsome was significantly higher than that of control for both trained groups. However, the stimulation of this enzyme activity was not changed by training intensity.
