Relation between Substance P-Immunoreactive Nerve Fibers and Lymphatic System in the Human Goukoku(LI4)-corresponding Area.
10.3777/jjsam.44.149
- VernacularTitle:ヒト合谷相当部におけるＳｕｂｓｔａｎｃｅ‐Ｐ陽性線維とリンパ系の関連について
- Author:
Kansho YAMADA
;
Takeshi HOSHINO
;
Nakazo WATARI
- Publication Type:Journal Article
- Keywords:
Acupoint;
SP-fiber;
Lymphatic vessel;
PSM;
Lymphatic system
- From:Journal of the Japan Society of Acupuncture and Moxibustion
1994;44(2):149-154
- CountryJapan
- Language:Japanese
-
Abstract:
Human skin sections of the Goukoku (LI·4)-corresponding area and its surroudings were collected and they were stained with H. E. dyes. Abundant nerve fibers and blood vessels were observed in the Goukoku (LI·4)-corresponding area, while their numbers were slightly decreased in the non-acupoint area on the meridian. Their numbers in the extra-meridian non-acupoint area were the lowest.
Substance P-containing nerve fibers were examined by histochemistry in the same areas, and many of them were observed in the Goukoku (LI·4)-corresponding area. And further more, they were closely associated with lymphatic vessels. These findings suggest the mechanism that Substance-P secreted by the stimulation of acupoint, is transported to the lymph node via lymphatic vessels, thus leading the stimulation of the lymphatic system.
Lymphatic vessels with abundant smooth muscles were predominantly noted in the Goukoku (LI·4)-corresponding area and scarcely in the non-acupoint area by fluorescent stain. This finding suggests that hypersensitive one may feel the contraction of lymphatic smooth muscle induced by the Substance-P as a phenomenon of propagated sensations along the meridians (PSM).
